Tripsas is a leading management scholar whose research and teaching focus on technological innovation and entrepreneurship. She studies how organizations can best adapt to new technologies that disrupt industries and ecosystems, with an emphasis on how the interplay of organizational capabilities, organizational identity, and managerial mental models shape strategic responses to technological shifts. She has studied the evolution of technology and competition in a diverse range of both established and nascent industries including photography/digital imaging, typesetters, air taxis, music synthesizers and publishing.