Oral Presentations

* denotes the technical presentation of a Grand Challenge contender
Monday, June 13, 2011 4:00pm - 5:00pm
TARTC
Time Title Presenter Authors
4-5pm Integrated Sensors for Wireless Non-contact Cardiac and Neural (ECG/EEG) Monitoring – TATRC Grand Challenge Yu Chi Yu Chi, Gert Cauwenberghs
4-5pm TATRC Challenge Awardees Presentation: Enhancing In-Field Detection of Protein Biological Warfare Agents via Aqueous Two-Phase Systems Foad Mashayekhi Foad Mashayekhi, Ricky Y.T. Chiu, Alexander M. Le, Parsa M. Nafisi, Benjamin M. Wu, Daniel T. Kamei
4-5pm Multimodal Imaging Probes for Diagnosis of Traumatic Brain Injury through Visualization of Activated Microglia (TATRC Challenge Awardees Presentation) Erica Andreozzi Erica Andreozzi, Angelique Louie, Bruce Lyeth
4-5pm An Injectable Decellularized Muscle Matrix for Skeletal Muscle Tissue Engineering and its Mitogenic Properties Jessica A. DeQuach Jessica A. DeQuach, Joy E. Lin, Cynthia Cam, Diane Hu, Karen L. Christman
4-5pm Biomaterials And Stem Cells For Nerve Regeneration Timothy L. Downing Eugene Zhu, Aijun Wang, Timothy L. Downing, Song Li
Tuesday, June 14, 2011 1:30pm - 2:50pm
Nanobiotechnology
Time Title Presenter Authors
1:30 Functional Structured Nanoemulsions Thomas G. Mason T.G. Mason, T.J. Deming, C.B. Chang, J.A. Hanson, M.M. Fryd
1:50 De novo design of bioactive protein-resembling nanospheres via dendrimer-templated peptide amphiphile assembly Rachel Marullo Rachel Marullo, Brian Lin, Matthew Tirrell
2:10 Protease Specificity Profiling Identifies Ligands that Substantially Increase Cleavage Rate and Protease Detection Sensitivity Abeer Jabaiah Abeer Jabaiah, Patrick S Daugherty
2:30 Protease-Resistant Peptide Ligands from a Stable Knottin Scaffold Library Jennifer Getz Jennifer A. Getz, Jeffrey J. Rice, and Patrick S. Daugherty
Bioinformatics
Time Title Presenter Authors
1:30 An Iterative Monte Carlo Simulation Algorithm Reveals Subtle Variations in Common Regulatory Motifs of Closely Related Transription Factors Phillip Seitzer Phillip Seitzer, Marc Facciotti
1:50 AESOP: Analysis of Electrostatic Similarities Of Proteins Chris A. Kieslich Ronald D. Gorham Jr., ZofiaGasik, Jan Antosiewicz, Dimitrios Morikis
Biomaterials
Time Title Presenter Authors
2:10 A selective mechanism of membrane destabilization by antimicrobial peptides based on negative Gaussian curvature generation Nathan W. Schmidt Nathan W. Schmidt, Abhijit Mishra, David Kuo, Ghee Hwee Lai, Gerard C. L. Wong
2:30 Interactions between cyclic cell penetrating peptides and lipid membranes Kun Zhao Kun Zhao, Tao Liu, Mike Choe, Daniel Kamei, Dehua Pei, Gerard Wong
Stem Cell Engineering
Time Title Presenter Authors
1:30 hear Alters the Proportion of Neural Crest versus Mesoderm-derived Osteoprogenitors in Embryoid Bodies Nicole zur Nieden Alexander Seeliger, Susanne Trettner, Susann Horvat, Julia Ast, Beatrice Kuske, Nicole I. zur Nieden
1:50 Microwells for Controlled and Uniform Embryoid Bodies Silin Sa Silin Sa, Diep Nguyen, Michelle Khine, Kara E. McCloskey
2:10 Mechanisms of Skeletal Muscle Differentiation via Organized Co-culture Technology Nikhil Rao Nikhil Rao, Katrina Spencer, Elliot Hui, Karen L. Christman
2:30 Controlled Matrix Elasticity Promotes Cardiac Differentiation Armin Arshi Armin Arshi, Yasuhiro Nakashima, Haruko Nakano, Atsushi Nakano
Imaging
Time Title Presenter Authors
1:30 Dual-mode Telemedicine Microscope Gabriel Biener Gabriel Biener, Alon Greenbaum, Serhan O. Isikman, Kelvin Lee, Derek Tseng, and Aydogan Ozcan
1:50 Quantitative Characterization of Peripheral Nerve Structural Features using Optical Coherence Tomography Michael C. Oliveira Md. Shahidul Islam, Xorge E. Alanis, Francis P. Henry, Johannes F. de Boer and B. Hyle Park
2:10 Simplified Four-Compartment Body Composition Model: Total Body Volume by DXA Joseph P Wilson Joseph P. Wilson, Jennifer L. Sherman, John A. Shepherd
2:30 Improving Specificity in Bright-Field Microscopy Images of the Beating Embryonic Heart Via Motion-Based Separation * Sandeep Bhat Sandeep Bhat, Michael Liebling
Tuesday, June 14, 2011 3:00pm - 5:00pm
Modeling
Time Title Presenter Authors
3:00 A New Multi-scale Platform For Investigating Peptide Self- Assembly Scott Carmichael Scott Carmichael, M. Scott Shell
3:20 Iterative Computational and Experimental Methods in Drug Design: The Paradigm of Compstatin Family Peptides Aliana López de Victoria Aliana López de Victoria, Ronald D. Gorham Jr., Phanourios Tamamis, Meghan L. Bellows-Peterson, Christodoulos A. Floudas, Georgios Archontis, Dimitrios Morikis
3:40 Predicting Subcutaneous Glucose Concentration for Type 1 Diabetes Using Empirical Models and Frequency-Band Separation Chunhui Zhao Chunhui Zhao, Eyal Dassau, Howard Zisser, Dale E. Seborg, Lois Jovanovič, Francis J. Doyle III
4:00 Computational design and characterisation of small gene networks with targeted behaviour in E. coli Alfonso Jaramillo Alfonson Jaramillo
4:20 Genetic Clocks from Engineered Oscillations Jeff Hasty Jeff Hasty
4:40 Semi-automated Artificial Pancreas using prandial inhaled insulin and Zone-Model Predictive Control * Justin Lee Justin Lee, Eyal Dassau, Howard Zisser, Lois Jovanovic, and Francis J. Doyle III
Biomaterials
Time Title Presenter Authors
3:00 Implication of membrane curvature generation by Influenza A virus M2 protein cytoplasmic helix in viral budding Abhijit Mishra Abhijit Mishra, Jun Wang, William F. DeGrado, Gerard C. L. Wong
3:20 The Structure and Application of Nucleic Acid-Surfactant Films for Transfection in Human Cells Sarah L. Perry Surekha Gajria, Sarah L. Perry, Jennifer Ni, John Weinstein, David Schaffer, Matt V. Tirrell
3:40 Understanding mechanisms by which injectable materials preserve cardiac function post-myocardial infarction Aboli Rane Aboli A. Rane, Joyce S. Chuang, Amul Shah, Diane P. Hu, Nancy D. Dalton, Yusu Gu, Kirk L. Peterson, Jeffrey H. Omens, Karen L. Christman
4:00 Development of Nanostructured Coatings for Controlling the Biodegradation of Magnesium Implants Maria Iskandar Maria Iskandar, Jaclyn Lock, Arash Aslani, Huinan Liu
4:20 Rapid isolation of high affinity aptamers through microfluidic SELEX technology and high-throughput sequencing analysis Minseon Cho Minseon Cho, Yi Xiao, Jeff Nie, Ron Stewart, Seung Soo Oh, James A. Thomson, H. Tom Soh
4:40 Rapid, Efficient Aptamer Generation: Kinetic Challenge-Microfluidic SELEX Seung Soo Oh Seung Soo Oh, Kareem M. Ahmad, Minseon Cho, Yi Xiao, H. Tom Soh
Biomechanics & Biophysics
Time Title Presenter Authors
3:00 Tunable brain-mimetic matrices for studying tumor mechanobiology and invasion Yushan Kim Yushan Kim, Badriprasad Ananthanarayanan, Sanjay Kumar
3:20 Three dimensional traction forces exerted by migrating amoeboid cells Begona Alvarez-Gonzalez Begona Alvarez-Gonzalez, Juan Carlos del Alamo, Ruedi Meili, Baldomero Alonso-Latorre, Richard Firtel, Juan C. Lasheras.
3:40 The Role of the Scar/WAVE Complex in the Mechanics of Cell Migration Effie Bastounis Effie Bastounis, Ruedi Meili, Baldomero Alonso-Latorre, Juan C. Del Alamo, Richard Firtel, Juan C. Lasheras
4:00 The Roles of N-cadherin in Three-dimensional Cancer Cell Invasion Wenting Shih Wenting Shih, Soichiro Yamada
4:20 Stick-slip behavior of Myxococcus Xanthus S motility observed by high-framerate microscopy and particle tracking algorithms. Maxsim Gibiansky Maxsim Gibiansky, William Hu, Fan Jin, Kun Zhao, Wenyuan Shi, Karin Dahmen, Gerard C. L. Wong
4:40 Bacteria use type-VI pili to ‘slingshot’ on surfaces Fan Jin Fan Jin, Jacinta C. Conrad, Maxsim L. Gibiansky, Gerard C. L. Wong
Imaging
Time Title Presenter Authors
3:00 Portable and Cost-effective Pixel Super-Resolution Microscope for Telemedicine Applications Waheb Bishara Waheb Bishara, Uzair Sikora, Onur Mudanyali, Ting-Wei Su, Oguzhan Yaglidere, Shirley Luckhart, Aydogan Ozcan
3:20 Ultrasound-Modulated Fluorescent Contrast Agent for Optical Detection of Cancer Lesions in Deep Tissue * Carolyn Schutt Carolyn Schutt, Michael Benchimol, Mark Hsu, Sadik Esener
3:40 Compound Coherent anti-Stokes Raman Scattering (CARS) microscope and Raman spectroscope for cellular lipid droplet analysis Iwan Schie Iwan W. Schie, Tyler Weeks, Li Jiang, Jian Wu, and Thomas Huser
4:00 Miniature integrated optical coherence tomography (OCT) - ultrasound (US) probe for intravascular imaging * Jiawen Li Jiawen Li, Jiehen Yi, Xiang Li, Joe Jing, David Mukai, Sari Mahon, Ahmad Edrisd, Khiet Hoang, K. Kirk Shung, Matthew Brenner, Jagat Narula, Qifa Zhou, and Zhongping Chen
4:20 Investigating Enzyme Activity with Hyperpolarized C-13 Metabolic Activity Decomposition MRI Christine Leon Leon, C, Larson, P, Kerr, A, Vigneron, D
4:40 Ultrafast Multipinhole Single Photon Emission Computed Tomography Iterative Reconstruction Using CUDA Fares Alhassen Fares Alhassen, Sangtaek Kim, George Sayre, Jason Bowen, Robert Gould, Youngho Seo
Wednesday, June 15, 2011 10:00am - 12:00pm
Biomedical Devices
Time Title Presenter Authors
10:00 A Portable Pneumatic Haptic Feedback System for Gait Rehabilitation in Peripheral Sensory Loss Zach McKinney Richard Fan, Zach McKinney, Warren Grundfest
10:20 An Optically Transparent, Gold-ITO-Hybrid Electrode Array for Integration of Electrocorticography with Optogenetic Techniques Peter Ledochowitsch Peter Ledochowitsch. Elisa Olivero, Michel M. Maharbiz
10:40 Ultra-High Sensitivity Doppler Variance Optical Coherence Tomography for Microvasculature Visualization Wenjuan Qi Wenjuan Qi, Gangjun Liu, Zhongping Chen
11:00 Structure-switching aptamer array for reagentless, label-free multiplexed detection of proteins in clinical samples * Seung Soo Oh Seung Soo Oh, Minseon Cho, H. Tom Soh
11:20 Lensless On-chip Microscope as a Portable Semen Analysis Device * Ting-Wei Su Ting-Wei Su, Anthony Erlinger, Derek Tseng, and Aydogan Ozcan
11:40 Field-portable Lensfree Reflection Holographic Microscopy Myungjun Lee Myungjun Lee and Aydogan Ozcan
Drug Delivery
Time Title Presenter Authors
10:00 Drug-Eluting Nanofibrous Patches Demonstrate Importance Of Release Kinetics In Spinal Cord Repair * Timothy L. Downing Timothy L. Downing, Aijun Wang, Zhi-Qiang Yan, Andy Lee, Song Li
10:20 Photothermally Triggered Drug Release from Temperature Sensitive Liposomes using Hollow Gold Nanoshells Tallie Forbes Tallie Forbes, Joseph A. Zasadzinski
10:40 Self-Assembled Micelles Containing Therapeutic Peptide Amphiphiles for Cancer Therapy Matthew Black Matthew Black, Matthew Tirrell
11:00 Enhanced Drug Delivery Efficacy Using a Transferrin Variant to Target Nanoparticles Ricky Y.T. Chiu Ricky Y.T. Chiu, Takuma Tsuji, Christina T. Liu, Anne B. Mason, Daniel T. Kamei
11:20 Replacing Microbubbles with Nanofluids: Development of Stable Ultrasound Triggered Drug Delivery Vehicles Stuart Ibsen Stuart Ibsen, Michael Benchimol, Dmitri Simberg, Sadik Esener
11:40 Microfluidic Brain Slice Chamber with Localized Injection Ports and Its Application to the Study of Cortical Spreading Depression Yujie Tanye Tang Yujie Tanye Tang, Héctor E. López-Valdés, KC Brennan, Y. Sungtaek Ju
Imaging
Time Title Presenter Authors
10:00 Lensfree On-chip Super Resolution Microscopy using Wetting-films Onur Mudanyali Onur Mudanyali, Waheb Bishara, Aydogan Ozcan
10:20 Lensfree Fluorescent Microscopy Ahmet F. Coskun Ting-Wei Su, Ikbal Sencan, Aydogan Ozcan
10:40 Portable magnetic tweezers device enables visualization of the 3-dimensional microscale deformation of soft biological materials Jun Lin Jun Lin, Yali Yang, Ryan Meschewski, Erin Watson & Megan T. Valentine
11:00 Biodistribution of PEGylated ICG-Loaded Polymeric Nanocapsules in Healthy Mice Baharak Bahmani Baharak Bahmani, Sharad Gupta, Valentine Vullev, Bahman Anvari
11:20 A Phase-sensitive Optical Coherence Tomography (OCT) Based Optical Electrode for Non-contact Neural Recording Md. Shahidul Islam M. Shahidul Islam, Christian Oh, Yan Wang, M. Rezuanul Haque, Michael C. Oliveira, B. Hyle Park
11:40 Lensfree Optical Tomographic Microscopy On a Chip Serhan Isikman Serhan O. Isikman, Waheb Bishara, Sam Mavandadi, Frank W. Yu, Steve Feng, Randy Lau and Aydogan Ozcan
Wednesday, June 15, 2011 2:00pm - 4:00pm
Biomedical Devices
Time Title Presenter Authors
2:00 Cost-effective and Field-portable Fluorescent Microscopy on a Cellphone Hongying Zhu Hongying Zhu, Oguzhan Yaglidere, Ting-Wei Su, Derek Tseng, and Aydogan Ozcan
2:20 Reducing Off-Chip Complexity of Microfluidic Devices with Integrated Pneumatic Digital Logic Transon Nguyen Transon V. Nguyen, Philip N. Duncan, Siavash Ahrar, Elliot E. Hui
Biosensors
Time Title Presenter Authors
2:40 The Development of a High Sensitive FRET-based Protease Assay for Kinetic Determination of SUMO-specific Protease – SENP1 Yan Liu Yan Liu, Yang Song, Vipul Madahar, Jiayu Liao
3:00 Sensing The Molecular World in Real Time Using Fluorescent and Electrochemical Biomolecular Switches Alexis Vallee-Belisle Vallee-Belisle, A., Ricci, F., Plaxco, K.W.
3:20 Microfluidic Electrochemical Aptameric Assay Integrated On-Chip: A Novel Sensing Platform for the Detecting Cell-secreted Cytokines Ying Liu Ying Liu, Jun Yan, Timothy Kwa, Michael Howland, Alexander Revzin
3:40 The Fundamental Limit of Implantable Electrochemical Glucose Sensors Kevin Louchis Kevin Louchis, Stephen O'Driscoll
Tissue Engineering
Time Title Presenter Authors
2:00 Lysophosphatidic Acid: A Novel Biochemical Agent for Tissue Engineering Fibrocartilage * Pasha Hadidi Pasha Hadidi, Kyriacos Athanasiou
2:20 Decellularized Human Lipoaspirate as a Minimally Invasive, Thermoresponsive Scaffold for Adipose Tissue Engineering D. Adam Young D. Adam Young, Dina O. Ibrahim, Karen L. Christman
2:40 Adaptation of Vascular Network Formation Assay to Reconfigurable Culture Platform David J. Li David J. Li, Dilip Dey, Gregory R.D. Evans, Elliot E. Hui
3:00 Exploration of Paracrine and Contact-Dependent Cell-Cell Signaling Within the Tumor Microenvironment Monica Y. Kim Monica Y. Kim, Katrina M. Spencer, Philip H. Suh, Andrew C. Newman, Christopher C. W. Hughes, Elliot E. Hui
3:20 Assessment of Keratinocyte and Fibroblast Migration on Fibrin and Collagen Matrices of Different Compositions on a 3D Skin Equivalent Wound Model Jessica Yang Jessica Yang, Benjamin Wu, Bill Tawil
3:40 Femtosecond Laser Ablation of Electrospun Poly(L-lactide) Nanofibrous Scaffolds Improves Cell Infiltration Benjamin Li-Ping Lee Benjamin Li-Ping Lee, Zhiqiang Yan, Hojeong Jeon, Costas Grigoropoulos, Song Li
Biomechanics & Biophysics
Time Title Presenter Authors
2:00 Bandpass Filtering of DNA Elastic Modes Using Confinement and Tension Jun Lin Jun Lin, Fredrik Persson, Joachim Fritzsche, Jonas O. Tegenfeldt, and Omar A. Saleh
2:20 Non-equilibrium fluctuations of cell membranes: The effect of cytoskeletal motor activity on membrane dynamics Roie Shlomovitz Roie Shlomovitz, Alex Levine
2:40 BAX and BCL-XL can induce complementary Gaussian membrane curvatures to regulate apoptotic pore formation Ghee Hwee Lai Ghee Hwee Lai, Olena Ivashyna, Lori Sanders, Eric Christenson, Abhijit Mishra, Nathan Schmidt, Kiyotaka Akabori, Christian Santangelo, Paul Schlesinger, Gerard C. L. Wong
3:00 Probing the directional structure and intracellular microrheology of eukaryotic cytoplasm Katie Osterday K. Osterday, M. Gómez, G. Norwich, S. Chien and J. C. del Álamo
3:20 3-D Surface Reconstruction and Strain Rate Levels of Both Tricuspid and Bicuspid Aortic Valves in Vitro Kai Szeto Kai Szeto, Javier Rodriguez, Peter Pastuszko, Vishal Nigam, & Juan C. Lasheras
3:40 Microfluidic Platform for Detecting Malaria Infected Avian Red Blood Cells William Tang Yu-Hsiang Hsu, Judy L. Coleman, William C. Tang
* denotes the technical presentation of a Grand Challenge contender
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